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Optogenetic activation of the dorsal raphe serotonergic neurons attenuates social and cognitive deficits in prenatal VPA mice To investigate whether ASD-like behavior in prenatal VPA mice is attenuated by the activation of DRN, we implanted an optical fiber in the DRN of TPH2-tTA::TetO-ChR2 tg mice, which is specifically expressed ChR2 in serotonergic neurons (Fig